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The current explosion of new areas of controversy in the treatment of acute lymphocytic leukemia in adults and young adults makes this comprehensive book a much needed reference for hematologists and oncologists. This book assembles leading authorities from around the globe to cover the full spectrum of ALL subtypes and their treatments. Specific topics of discussion include indications for allogeneic bone marrow transplant in first complete remission, the role of minimal residual disease in making treatment decisions, the treatment of young adults, and the treatment of Philadelphia chromosome positive ALL with the advent of the tyrosine kinase inhibitors. This is the first book to focus exclusively on the adult ALL patient. It provides a complete overview of diagnosis, molecular pathogenesis, evaluation, and treatment for this important patient population.
This volume enables students to master the science and clinical applications of hematologic pathophysiology and develop the problem-solving skills that are needed for exams and clinical rotations. The book provides a solid overview of hematology and applies scientific principles to actual clinical cases and problems. This unique “case-problem” format prepares students to link basic science to clinical medicine as emphasized in today’s exams.Using actual patient cases to illustrate hematologic principles, the book covers the life cycles, structures, and physiology of red and white blood cells and then discusses hemostasis, bone marrow disorders, and hematologic malignancies. Boxed case-problems challenge the student to apply key hematologic principles in a variety of clinical decisions. Numerous two-color drawings and schematics illustrate all essential concepts, and subheads, color highlights, and tables aid in comprehension and review.
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